- May 1 147th Kentucky Derby: Medina Spirit gives jockey John Velazquez his fourth Derby win and trainer Bob Baffert a record seventh victory in the race
- May 3 World Snooker Championship, Crucible Theatre, Sheffield: Englishman Mark Selby wins his 4th world title with an 18-15 win over countryman Shaun Murphy
- May 4 Following several positive Covid-19 cases across franchises the BCCI announces the indefinite postponement of the Indian Premier League cricket tournament
- May 5 Baltimore Orioles pitcher John Means no-hits Seattle Mariners, 6-0 at T-Mobile Park, Seattle
- May 7 Cincinnati Reds pitcher Wade Miley no-hits Cleveland Indians, 3-0 at Progressive Field, Cleveland
- May 18 Detroit Tigers pitcher Spencer Turnbull no-hits Seattle Mariners, 5-0 at Comerica Park, Detroit
- May 19 New York Yankees pitcher Cory Kluber no-hits Texas Rangers, 2-0 at Globe Life Field, Arlington, Texas
- May 22 30-year-old Scottish light-welterweight boxer Josh Taylor becomes Britain's first undisputed world champion in the four-belt era by beating Jose Ramirez by unanimous decision in Las Vegas
PGA Championship
May 23 PGA Championship Men's Golf, Ocean Course Kiawah Island: Phil Mickelson becomes oldest major winner in history (50); wins his 6th major by 2 strokes over Brooks Koepka and Louis Oosthuizen
- May 29 UEFA Champions League Final, Porto: Kai Havertz scores just before halftime to give Chelsea a 1-0 win over Manchester City in an all-English final; Blues' second CL title
- May 30 Indianapolis 500: Brazilian Hélio Castroneves wins his record 4th title in 2:37:19.3846; new record for fastest running of the race with average speed 190.690 mph
Osaka Leaves the French Open
May 31 Naomi Osaka pulls out of the French Open citing her mental health, after refusing to appear at compulsory post match press conferences
Baseball Players
Basketball Stars
Boxers
Footballers
NFL Stars
Tennis Champions