- Jan 6 Charley O'Leary, American baseball shortstop (Detroit Tigers; oldest MLB player to collect a hit and score a run [58] St. Louis Browns 1934), dies at 65
- Jan 11 Emanuel Lasker, German chess player (b. 1868)
- Jan 24 Tommy Bond, Irish baseball pitcher and right fielder (Triple Crown 1877; Boston Red Caps; first man born in Ireland to play MLB), dies at 84
Lou Gehrig (1903-1941)
Jun 2 American Baseball Hall of Fame first baseman (6 x World Series, 2 x AL MVP; 7 x MLB All Star; NY Yankees), dies of Amyotrophic Lateral Sclerosis (ALS), a disorder now commonly referred to as Lou Gehrig's Disease at 37
- Jun 3 Andy Cooper, American Baseball HOF pitcher (East-West All-Star 1933, 36; Negro NL pennant 1929; 3 x Negro AL pennants; Detroit Stars, Kansas City Monarchs), dies from a heart attack at 44
- Jun 6 Louis Chevrolet, Swiss auto racer (co-founder Chevrolet Motor Car Company), dies of a heart attack at 62
- Jul 30 Mickey Welch, American Baseball HOF pitcher (third to 300 career wins; Troy Trojans, New York Giants), dies from complications of gangrene of the foot at 82
- Aug 12 Bobby Peel, English cricket all-rounder (20 Tests, 3 x 50, 101 wickets, BB 7/31; Yorkshire CCC), dies at 84
- Aug 23 Jack O'Connor, Australian cricket fast bowler (4 Tests, 13 wickets, BB 5/40; NSW CA, SA CA), dies at 65
- Sep 1 Benjamin Dwight, American tennis championship umpire, dies
- Oct 20 Ken Farnes, English cricket fast bowler (15 Tests, 60 wickets, BB 6/96; Essex CCC, Cambridge University CC), dies in a plane crash during a WWII night-flying exercise at 30
- Oct 29 Harvey Hendrick, American baseball player (b. 1897)
- Nov 12 Ernie Koob, American baseball pitcher (no-hitter 1917; St. Louis Browns), dies from a lung ailment at 49
- Dec 1 Horace Chapman, South African cricket all-rounder (2 Tests, 1 wicket; Natal), dies at 51
- Dec 8 Frank "Pop" Morgenweck, American Basketball HOF contributor (team owner/coach in 18 cities), dies at 66
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