- Sep 4 15-year-old cyclist Doris Kopsky becomes 1st Amateur Bicycle League of America woman's national champion in 4:22.4 in Buffalo, NY
- Sep 10 2nd American Football League plays 1st game (LA 21, Pittsburgh 0)
- Sep 10 Cleveland (Los Angeles) Rams plays their 1st NFL game, lose 28-0
- Sep 11 US National Championship Men's Tennis, Forest Hills, NY: American Don Budge wins first of 2 straight US titles; beats Gottfried von Cramm of Germany 6-1, 7-9, 6-1, 3-6, 6-1
- Sep 11 US National Championship Women's Tennis, Forest Hills, NY: Anita Lizana of Chile becomes first Latin American to win a major; beats Jadwiga Jędrzejowska of Poland 6-4, 6-2
Redskins First Game
Sep 16 Redskins NFL franchise play first game in Washington at Griffith Stadium; defeat the New York Giants in season opener, 13–3
- Sep 17 1st NFL game in Washington, D.C.; Redskins beat NY Giants 13-3
- Sep 23 Yankees lose 9-5 but clinch pennant when Red Sox beat Detroit
- Sep 29 Frans Slaats cycles a world hour record time (45,563 km)
- Sep 30 Ryder Cup Golf, Southport & Ainsdale GC: US wins 8-4; first time the host team loses the competition