- Sep 2 International Lawn Tennis Challenge, NYC, NY: Bill Johnson beats John Hawkes 6-0, 6-2, 6-1 for unassailable 3-1 lead for US over Australia; ends 4-1; US 4th straight win
- Sep 4 New York Yankees pitcher "Sad" Sam Jones no-hits Philadelphia A's, 2-0
- Sep 5 Flyweights Gene LaRue & Kid Pancho KO each other simultaneously
Dempsey KOs Firpo
Sep 14 In his 4th heavyweight boxing title defence Jack Dempsey recovers after being sent through the ropes to KO Argentine challenger Luis Firpo in the 2nd round at the Polo Grounds, NYC
- Sep 14 Red Sox 1st baseman George Burns pulls off an unassisted triple play
US Men's Tennis Open
Sep 15 US National Championship Men's Tennis, Germantown CC, Philadelphia: Bill Tilden wins 4th of 6 straight US singles titles; beats Bill Johnston 6-4, 6-1, 6-4
Lou Gehrig's 1st HR
Sep 27 NY Yankee Lou Gehrig hits 1st of his 493 HRs
- Sep 28 New York Yankees overwhelm Boston Red Sox 24-4
PGA Championship
Sep 29 PGA Championship Men's Golf, Pelham CC: Defending champion Gene Sarazen beats Walter Hagan in 38 holes for 3rd of his 7 major titles