- May 1 Henry Cooper, English boxer (British, European, C'wealth heavyweight champion; famous defeats to Muhammad Ali 1963, 66), dies of heart failure at 76
- May 1 Ted Lowe, English snooker commentator (Pot Black, BBC), dies at 90
- May 3 Sergo Kotrikadze, Georgian footballer (b. 1936)
- May 5 Yosef Merimovich, Israeli football player, 1948-58, and manager, 1958-89, dies at 86
Seve Ballesteros (1957-2011)
May 7 Spanish golfer (British Open 1979, 84, 88, US Masters 1980, 83), dies of brain cancer at 54
Harmon Killebrew (1936-2011)
May 17 American Baseball HOF utility (13 × MLB All-Star; AL MVP 1969; 6 × AL HR leader; Washington Senators, Minnesota Twins), dies from esophageal cancer at 74
- May 25 Paul Splittorff, American MLB pitcher and broadcaster (KC Royals), dies of oral cancer at 64
- May 25 Terry Jenner, Australian cricket spin bowler (9 Tests, 24 wickets; WA CA, SA CA), dies from a heart attack at 66
- May 27 Margo Dydek, Polish basketball player (b. 1974)
- May 29 William "Bill" Roycroft, Australian equestrian 3 day (Olympic bronze 1976), dies at 96
- May 31 Andy Robustelli, American NFL defensive end (LA Rams, NY Giants), dies at 85
- May 31 Pauline Betz Addie, American tennis player (5 Grand Slam singles titles), dies of complications from Parkinson's disease at 91